101 Case Studies for Anatomy and Physiology

Author(s): Charlotte Russell

Edition: 2

Copyright: 2022

Pages: 242

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$54.69 USD

ISBN 9781792491290

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The purpose of this compendium of case studies is to provide both instructors and students the opportunity to utilize case studies in furthering that medical knowledge and instruction. For instructors, these case studies provide a useful tool, especially when new to teaching anatomy and physiology. Utilizing active learning is one of the best proven ways for students to learn, allowing them to further investigate a concept to enhance understanding, application of knowledge, and then begin developing the skills required for diagnostics. To guide students through the main topics of Anatomy and Physiology, the case studies are firstly organized on the basis of the order that systems are presented in most textbooks. This enables case studies to be easily extracted for use when discussing a particular system, or aspect. Case studies can be used for other systems as it is know that all systems work in concert and not in isolation, so while a case study may be used in one context, questions are provided that also allow cases to be used with different emphases. The questions that accompany each clinical scenario follow the same format, and allow the case scenario to be used to introduce, reinforce, and explore content and concepts. In this compendium, the questions are based on three primary outcomes: (1) Conceptualization, (2) Analyze and Apply, and (3) Diagnose. Students have the opportunity to use content that has been introduced to them in the class setting but also explore by researching the topic to gain further understanding of management, prescription, and complexities of the clinical scenarios. Each case has been fully researched to ensure that the information is clinically accurate and the management of patients is realistic to current guidelines.

Preface
Acknowledgments
About the Author 

CHAPTER 1: GENERAL MEDICINE 
1. Chronic Fatigue Syndrome 
2. histopathology 
3. Misalignment of Sample / Biopsy 
CHAPTER 2: THE INTEGUMENT 
4. Alopecia 
5. Burns 
6. Compartment Syndrome 
7. Scleroderma 
8. Systemic Lupus Erythematosus 
9. Skin Cancer–Malignant Melanoma 
10. Wound Healing 
11. Wound Healing 2 
CHAPTER 3: THE SKELETON–BONE 
12. Fibrodysplasia Ossificans Progressiva 
13. Fractures no Complications 
14. Fracture wt Complications (osteomyelitis) 
15. Fracture wt complications (fat emboli) 
16. Osteomalacia 
17. Osteogenesis imperfecta 
18. Osteoporosis 
19. Pagets 
20. Scoliosis 
CHAPTER 4: THE SKELETON–JOINTS 
21. Ankylosing Spondylitis 
22. Anterior Cruciate Ligament Tear 
23. Craniosynostosis 
24. Osteoarthritis 
25. Pectus Excavatum 
26. Rheumatoid Arthritis 
CHAPTER 5: THE MUSCULAR SYSTEM—MUSCULAR AND
NEUROMUSCULAR DISORDERS 

Muscular 
27. Malignant Hyperthermia 
28. Muscular Dystrophy 
29. Myasthenia Gravis 
30. Rhabomyolysis and Myoglobinuria 
Neuromuscular 
31. Amylotrophic Lateral Sclerosis (ALS) 
32. Multiple Sclerosis 
33. Spinal Muscular Atrophy
CHAPTER 6: THE CENTRAL, PERIPHERAL, AND AUTONOMIC
NERVOUS SYSTEMS 

34. Alzheimer’s Disease 
35. Concussive Injury/PCS 
36. Epidural Hematoma 
37. Huntingtons Disease 
38. Meningitis 
39. Neurocardiogenic Syncope 
40. Parkinson’s 
41. Postural Orthostatic Tachycardia Syndrome 
42. Spinal Cord Injury (1) 
43. Spinal Cord Injury (2) 
44. Stroke 
CHAPTER 7: THE SPECIAL SENSES 
45. Acute Angle Glaucoma 
46. Fibromyalgia 
47. Meniere’s 
48. Otitis Media 
49. Retinal Detachment 
CHAPTER 8: THE ENDOCRINE SYSTEM 
50. Acromegaly 
51. Addison’s 
52. Cushing’s 
53. Graves Disease 
54. Growth Hormone Deficiency 
55. Hashimotos 
56. Secondary Hypergonadotrophic Hypergonadism/Delayed onset Puberty 
57. Type I DM 
58. Type II DM 
CHAPTER 9: THE CARDIOVASCULAR SYSTEM–BLOOD 
59. Deep Vein Thrombosis 
60. Hemochromatosis 
61. Iron Deficient Anemia 
62. Leukemia AML 
63. Leukemia CLL 
64. Polycythemia vera 
65. Porphyria 
66. Sickle Cell Trait 
67. Vit K Deficiency 
CHAPTER 10: THE CARDIOVASCULAR SYSTEM–THE HEART 
68. Acute Bacterial Pericarditis 
69. Atrial Septal Defect (secundum) 
70. Myocardial Infarction–Female 
71. Rheumatic fever / Valvular stenosis 
72. Sick Sinus Syndrome 
73. Transient NSTEMI 
CHAPTER 11: THE CARDIOVASCULAR SYSTEM–BLOOD VESSELS 
74. Cerebral Aneurysm 
75. Hypovolemic Shock 
76. Occlusive Peripheral Arterial Disease 
77. Portal Hypertension 
78. Thromboangiitis Oliterans (Buergers Disease) 
CHAPTER 12: THE LYMPHATIC SYSTEM 
79. Hodgkins Lymphoma 
80. Lymphangitis 
vi Table of Contents
81. Lymphedema 
82. Non-hodgkins Lymphoma 
CHAPTER 13: THE IMMUNE SYSTEM 
83. Anaphylaxis 
84. Leptospirosis 
85. Multi inflammatory Syndrome–Children (MIS-C) 
86. PANDAS 
87. Splenectomy 
CHAPTER 14: THE RESPIRATORY SYSTEM 
88. Carbon Monoxide Poisoning 
89. COPD 
90. Bacterial Pneumonia with Emphysema 
91. Pneumonia with Pleural Effusion/Empyema 
92. Pulmonary Sarcoidosis 
93. Tension Pneumothorax 
CHAPTER 15: THE DIGESTIVE SYSTEM 
94. Acute Pancreatitis 
95. Appendicitis 
96. Celiac 
97. Crohns 
98. Obstructive Jaundice 
CHAPTER 16: THE URINARY SYSTEM 
99. Acute Kidney Injury (AIN)—NSAIDS 
100. Acute kidney stones–Oxacelate Crystals 
101. Bladder stones 
102. Chronic Kidney Disease–Dialysis 
103. UTI 
CHAPTER 17: NUTRITION AND HOMEOSTASIS 
104. Diabetes Insipidus 
105. Heat Stroke 
106. Kwashiorkor (malnutrition) 
107. Marasmus (malnutrition) 
108. Water Intoxication 
CHAPTER 18: THE REPRODUCTIVE SYSTEMS 
109. Endometriosis 
110. Enlarged prostate 
111. Fibroids 
112. Polycystic Ovarian Syndrome 
113. Testicular Torsion 
CHAPTER 19: HUMAN DEVELOPMENT 
114. Cerebral palsy 
115. Chorioamnionitis 
116. Twin-Twin Transfusion syndrome 
117. Gestational diabetes 
118. Pre-eclampsia 
119. Spina bifida 
120. Gastroschisis 
APPENDIX 

Charlotte Russell

Charlotte Russell was trained in England, first receiving her Baccalaureate in Medical Sciences from the University of Birmingham. She then went on to receive her PhD in Cell Biology and Molecular Medicine from the University of Manchester. Prior to emigrating to the United States, she completed her post-doc-toral fellowship in the Department of Cardiovascular Biology at Kings College London under the tutelage of Professor Jeremy Pearson, MBE. On moving to the US, Dr Russell has been teaching at Simmons University (formerly Simmons College) in the Biology department since 2006, teaching primarily Anatomy and Physiology to those going into clinical medicine professions, most notably under-graduates in the Nursing program. Additionally, Dr Russell has taught at Harvard Medical School as an adjunct instructor for Gross Anatomy and Histology for the medical and dental students. From her training, Dr Russell has broad knowledge in all areas of Human Biology, though her loves and scholarly interests are more in Cardiovascular Biology, Endocrinology, and Reproductive Biology.
Dr Russell has been using clinical case studies from the very beginning to enhance student learning; helping students to develop their conceptual understanding and diagnostic skills. This compilation of case studies has come about through bringing together all the cases she has developed throughout her teaching career, and others that she has written specifically for this publication to expand on the options available to other educators. When starting out in teaching, Dr Russell found having access to existing case studies invaluable and so hopes that this book will do the same for other educators starting out teaching in the medical sciences.

The purpose of this compendium of case studies is to provide both instructors and students the opportunity to utilize case studies in furthering that medical knowledge and instruction. For instructors, these case studies provide a useful tool, especially when new to teaching anatomy and physiology. Utilizing active learning is one of the best proven ways for students to learn, allowing them to further investigate a concept to enhance understanding, application of knowledge, and then begin developing the skills required for diagnostics. To guide students through the main topics of Anatomy and Physiology, the case studies are firstly organized on the basis of the order that systems are presented in most textbooks. This enables case studies to be easily extracted for use when discussing a particular system, or aspect. Case studies can be used for other systems as it is know that all systems work in concert and not in isolation, so while a case study may be used in one context, questions are provided that also allow cases to be used with different emphases. The questions that accompany each clinical scenario follow the same format, and allow the case scenario to be used to introduce, reinforce, and explore content and concepts. In this compendium, the questions are based on three primary outcomes: (1) Conceptualization, (2) Analyze and Apply, and (3) Diagnose. Students have the opportunity to use content that has been introduced to them in the class setting but also explore by researching the topic to gain further understanding of management, prescription, and complexities of the clinical scenarios. Each case has been fully researched to ensure that the information is clinically accurate and the management of patients is realistic to current guidelines.

Preface
Acknowledgments
About the Author 

CHAPTER 1: GENERAL MEDICINE 
1. Chronic Fatigue Syndrome 
2. histopathology 
3. Misalignment of Sample / Biopsy 
CHAPTER 2: THE INTEGUMENT 
4. Alopecia 
5. Burns 
6. Compartment Syndrome 
7. Scleroderma 
8. Systemic Lupus Erythematosus 
9. Skin Cancer–Malignant Melanoma 
10. Wound Healing 
11. Wound Healing 2 
CHAPTER 3: THE SKELETON–BONE 
12. Fibrodysplasia Ossificans Progressiva 
13. Fractures no Complications 
14. Fracture wt Complications (osteomyelitis) 
15. Fracture wt complications (fat emboli) 
16. Osteomalacia 
17. Osteogenesis imperfecta 
18. Osteoporosis 
19. Pagets 
20. Scoliosis 
CHAPTER 4: THE SKELETON–JOINTS 
21. Ankylosing Spondylitis 
22. Anterior Cruciate Ligament Tear 
23. Craniosynostosis 
24. Osteoarthritis 
25. Pectus Excavatum 
26. Rheumatoid Arthritis 
CHAPTER 5: THE MUSCULAR SYSTEM—MUSCULAR AND
NEUROMUSCULAR DISORDERS 

Muscular 
27. Malignant Hyperthermia 
28. Muscular Dystrophy 
29. Myasthenia Gravis 
30. Rhabomyolysis and Myoglobinuria 
Neuromuscular 
31. Amylotrophic Lateral Sclerosis (ALS) 
32. Multiple Sclerosis 
33. Spinal Muscular Atrophy
CHAPTER 6: THE CENTRAL, PERIPHERAL, AND AUTONOMIC
NERVOUS SYSTEMS 

34. Alzheimer’s Disease 
35. Concussive Injury/PCS 
36. Epidural Hematoma 
37. Huntingtons Disease 
38. Meningitis 
39. Neurocardiogenic Syncope 
40. Parkinson’s 
41. Postural Orthostatic Tachycardia Syndrome 
42. Spinal Cord Injury (1) 
43. Spinal Cord Injury (2) 
44. Stroke 
CHAPTER 7: THE SPECIAL SENSES 
45. Acute Angle Glaucoma 
46. Fibromyalgia 
47. Meniere’s 
48. Otitis Media 
49. Retinal Detachment 
CHAPTER 8: THE ENDOCRINE SYSTEM 
50. Acromegaly 
51. Addison’s 
52. Cushing’s 
53. Graves Disease 
54. Growth Hormone Deficiency 
55. Hashimotos 
56. Secondary Hypergonadotrophic Hypergonadism/Delayed onset Puberty 
57. Type I DM 
58. Type II DM 
CHAPTER 9: THE CARDIOVASCULAR SYSTEM–BLOOD 
59. Deep Vein Thrombosis 
60. Hemochromatosis 
61. Iron Deficient Anemia 
62. Leukemia AML 
63. Leukemia CLL 
64. Polycythemia vera 
65. Porphyria 
66. Sickle Cell Trait 
67. Vit K Deficiency 
CHAPTER 10: THE CARDIOVASCULAR SYSTEM–THE HEART 
68. Acute Bacterial Pericarditis 
69. Atrial Septal Defect (secundum) 
70. Myocardial Infarction–Female 
71. Rheumatic fever / Valvular stenosis 
72. Sick Sinus Syndrome 
73. Transient NSTEMI 
CHAPTER 11: THE CARDIOVASCULAR SYSTEM–BLOOD VESSELS 
74. Cerebral Aneurysm 
75. Hypovolemic Shock 
76. Occlusive Peripheral Arterial Disease 
77. Portal Hypertension 
78. Thromboangiitis Oliterans (Buergers Disease) 
CHAPTER 12: THE LYMPHATIC SYSTEM 
79. Hodgkins Lymphoma 
80. Lymphangitis 
vi Table of Contents
81. Lymphedema 
82. Non-hodgkins Lymphoma 
CHAPTER 13: THE IMMUNE SYSTEM 
83. Anaphylaxis 
84. Leptospirosis 
85. Multi inflammatory Syndrome–Children (MIS-C) 
86. PANDAS 
87. Splenectomy 
CHAPTER 14: THE RESPIRATORY SYSTEM 
88. Carbon Monoxide Poisoning 
89. COPD 
90. Bacterial Pneumonia with Emphysema 
91. Pneumonia with Pleural Effusion/Empyema 
92. Pulmonary Sarcoidosis 
93. Tension Pneumothorax 
CHAPTER 15: THE DIGESTIVE SYSTEM 
94. Acute Pancreatitis 
95. Appendicitis 
96. Celiac 
97. Crohns 
98. Obstructive Jaundice 
CHAPTER 16: THE URINARY SYSTEM 
99. Acute Kidney Injury (AIN)—NSAIDS 
100. Acute kidney stones–Oxacelate Crystals 
101. Bladder stones 
102. Chronic Kidney Disease–Dialysis 
103. UTI 
CHAPTER 17: NUTRITION AND HOMEOSTASIS 
104. Diabetes Insipidus 
105. Heat Stroke 
106. Kwashiorkor (malnutrition) 
107. Marasmus (malnutrition) 
108. Water Intoxication 
CHAPTER 18: THE REPRODUCTIVE SYSTEMS 
109. Endometriosis 
110. Enlarged prostate 
111. Fibroids 
112. Polycystic Ovarian Syndrome 
113. Testicular Torsion 
CHAPTER 19: HUMAN DEVELOPMENT 
114. Cerebral palsy 
115. Chorioamnionitis 
116. Twin-Twin Transfusion syndrome 
117. Gestational diabetes 
118. Pre-eclampsia 
119. Spina bifida 
120. Gastroschisis 
APPENDIX 

Charlotte Russell

Charlotte Russell was trained in England, first receiving her Baccalaureate in Medical Sciences from the University of Birmingham. She then went on to receive her PhD in Cell Biology and Molecular Medicine from the University of Manchester. Prior to emigrating to the United States, she completed her post-doc-toral fellowship in the Department of Cardiovascular Biology at Kings College London under the tutelage of Professor Jeremy Pearson, MBE. On moving to the US, Dr Russell has been teaching at Simmons University (formerly Simmons College) in the Biology department since 2006, teaching primarily Anatomy and Physiology to those going into clinical medicine professions, most notably under-graduates in the Nursing program. Additionally, Dr Russell has taught at Harvard Medical School as an adjunct instructor for Gross Anatomy and Histology for the medical and dental students. From her training, Dr Russell has broad knowledge in all areas of Human Biology, though her loves and scholarly interests are more in Cardiovascular Biology, Endocrinology, and Reproductive Biology.
Dr Russell has been using clinical case studies from the very beginning to enhance student learning; helping students to develop their conceptual understanding and diagnostic skills. This compilation of case studies has come about through bringing together all the cases she has developed throughout her teaching career, and others that she has written specifically for this publication to expand on the options available to other educators. When starting out in teaching, Dr Russell found having access to existing case studies invaluable and so hopes that this book will do the same for other educators starting out teaching in the medical sciences.