CHEM 3010/3020: Laboratory Exercises for Organic Chemistry

Introduction 
Laboratory Safety 
Chemical Hazard Information 
Notebooks and Reports 
The Laboratory Notebook 
Laboratory Reports 
Literature of Organic Chemistry 
How to Use Chemical Abstracts 
How to Use Beilstein 

Experiments
1. Effect of Impurities on Melting Range 
2. Melting Point Determination for Identification 
3. Recrystallization 
4. Distillation of a Binary Mixture 
5. Preparation of Absolute Alcohol by Azeotropic Distillation 
6. Determination of a Partition Coefficient for Extraction 
7. Separation of a Mixture by Extraction 
8. Separations 
9. TLC Analysis of Analgesic Tablets 
10. Oxymercuration-Demercuration of an Alkene 
11. Radical Bromination of a Hydrocarbon 
12. Microscale Chlorination of a Hydrocarbon 
13. Structural Effects on SN1 and SN2 Reactivity 
14. Solvent and Temperature Effects in Nucleophilic Substitution 
15. Green Oxidation of an Alkene 
16. Alkene Preparation via Alcohol Dehydration 
17. Hypochlorite Oxidation of an Alcohol
18. Oxidation of an Alcohol to a Carboxylic Acid 
19. Grignard Reaction 
20. Literature Search Problem #1 
21. Literature Search Problem #2 
22. Fischer Esterification 
23. Determination of Keq for Esterification 
24. Diels-Alder Reaction: Maleic Anhydride & Sulfolene 
25. Diels-Alder Reaction: Maleic Anhydride & Anthracene 
26. Reduction of an Aldehyde or Ketone 
27. Reduction of a Nitro Group to an Amine 
28. Preparation of an Acetamide 
29. Amide Preparation via the Acid Chloride 
30. Aldol Condensation 
31. Aromatic Nitration 
32. Nitration of a Substituted Aromatic Compound 
33. Friedel-Crafts Reaction 
34. Isolation of an Essential Oil 
35. Stereochemistry of Alkene Addition 
36. Chemistry of Aldehydes and Ketones 

Qualitative Organic Analysis 
          Physical Examination 
          Physical Constants 
          Solubility Tests 
          Functional Group Tests 
          Structural Information Tests 
          Preparation of Derivatives 
          Qualitative Analysis Report Format 
          Tables of Derivatives