CHEM 3010/3020: Laboratory Exercises for Organic Chemistry

Introduction 
Laboratory Safety 
Chemical Hazard Information 
Notebooks and Reports 
The Laboratory Notebook 
Laboratory Reports 

Experiments
1. Effect of Impurities on Melting Range 
2. Melting Point Determination for Identification 
3. Recrystallization 
4. Distillation of a Binary Mixture 
5. Separation of a Mixture by Extraction 
6. Extraction of Caffeine from Tea 
7. Separations 
8. TLC Analysis of Analgesic Tablets 
9. Radical Bromination of a Hydrocarbon 
10. Structural Effects on SN1 and SN2 Reactivity 
11. Solvent and Temperature Effects in Nucleophilic Substitution 
12. Alkene Preparation via Alcohol Dehydration 
13. Stereochemistry of Alkene Addition 
14. Hypochlorite Oxidation of an Alcohol
15. Oxidation of an Alcohol to a Carboxylic Acid 
16. Reduction of an Aldehyde or Ketone 
17. Diels-Alder Reaction: Maleic Anhydride & Sulfolene 
18. Diels-Alder Reaction: Maleic Anhydride & Anthracene 
19. Aromatic Nitration 
20. Nitration of a Substituted Aromatic Compound 
21. Friedel-Crafts Reaction 
22. Chemistry of Aldehydes and Ketones 
23. Fischer Esterification 
24. Determination of Keq for Esterification 
25. Preparation of an Acetamide 
26. Reduction of a Nitro Group to an Amine 
27. Aldol Condensation 
28. Isolation of an Essential Oil 

LIST OF TABLES
1. Known Compounds for Melting Point Experiments 
2. Compounds for Distillation Mixtures 
3. Aldehydes, Ketones & Derivatives 
4. Melting Points of Crossed Aldol Products 

LIST OF FIGURES
1. Melting Point Devices
2. Microscale Distillation Setup
3. Microscale Extraction 
4. Microscale Bromination Apparatus 
5. Microscale Dehydration Setups 
6. Microscale Reflux Apparatus 
7. Microscale Reflux with Addition 
8. Esterification Apparatus
9. Dean-Stark Apparatus