Unit 1: Atoms to Molecules; The Fundamentals of Bonding
Electronegativity and bonding, atomic and hybridized orbitals, molecular orbitals, three-dimensional Lewis structures, and resonance.
Unit 2: The Structure of Organic Molecules
Nomenclature, functional groups, intermolecular forces and solubility, conformational isomerism and strain in acyclic and cyclic molecules, cyclohexane as a chair, chirality, stereoisomerism, and relationships between molecules.
Units 3: Introduction to Organic Reactions
Acid-base chemistry, resonance, identifying nucleophiles and electrophiles, and drawing curved arrows in organic reactions.
Unit 4: Electrophilic Addition to Alkenes and Alkynes
Thermodynamics and kinetics of organic reactions, alkene and carbocation stability, and reactions, mechanisms and stereochemical considerations of regioselective electrophilic addition reactions to alkenes and alkynes. Application through energy diagrams, predicting the products, and multistep synthesis.
Unit 5: Introduction to Substitution and Elimination of Halides
Comparisons between nucleophilic substitution reactions (SN1 and SN2) and elimination reactions (E1 and E2) of alkyl halides and factors that influence these reactions, including transition state stabilization, nucleophilicity, and solvent effects
Unit 6: Substitution and Elimination of Alcohols, Ether, and Epoxides
Nucleophilic substitution reactions (SN1 and SN2) and elimination reactions (E1 and E2) of alcohols, ethers, and epoxides; acid-base chemistry of organometallic reagents; and using organolithium and Grignard reagents to make carbon-carbon bonds.
Unit 7: Introduction to Radical Reactions in Organic Chemistry
Radical substitution and addition reactions, including relative reactivity and selectivity of halide radicals in C-H substitution reactions.