Making "Sense" of Genetics Today
Edition: 1
Copyright: 2025
Pages: 206
Edition: 1
Copyright: 2025
Pages: 100
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Making “Sense” of Genetics Today – Karl Chai
- This book returns the Law of Genetics to its simple core in the original discovery and in the applications to genetic studies over the past 120 years, as well as that of today.
- Using classic human hereditary disorders as examples, such as alkaptonuria, sickle cell anemia, Huntington Disease, and cystic fibrosis, the methods of determining the molecular genetic basis of such diseases are outlined.
- The genetics principle at play behind the modern-day “genome-wide association studies” and the variations on the theme is explained for a more sensible and careful evaluation of the findings.
- It provides an overview on some state-of-the-art applications of genetics in modern medicine, and an outlook on the tasks ahead and benefits to expect for mankind.
The book is appropriate for interested readers ranging from students taking genetics courses in high school or college, to scientists and clinicians making sense of the findings from genetic studies.
Karl X. Chai, Ph.D. is a professor at the University of Central Florida, where he has taught Molecular Biology since 1996 and Human Genetics since 2010. He is the author of Interpretive Molecular Biology (2nd ed., 2026) and Making “Sense” of Genetics Today (2024). His research spans human gene cloning, genomics, and epigenetics, including work involving the human kallistatin and B1 bradykinin receptor genes. Dr. Chai earned his Ph.D. in Biochemistry and Molecular Biology from the Medical University of South Carolina and his B.S. in Biochemistry from Peking University.
- B.S. in Biochemistry, 1985, Peking University, Beijing, China
- CUSBEA Class V, 1985 (China-US Biochemistry Examination and Application)
- Ph.D. in Biochemistry and Molecular Biology, 1992, Medical University of South Carolina (MUSC), Charleston
- Postdoctoral fellow, molecular genetics of hypertension, 1992-1996, MUSC
- Molecular cloning of the human kallistatin (PI4/SERPINA4) cDNA and gene
- Assistant Professor - Associate Professor, 1996-present, University of Central Florida (UCF) (College of Medicine)
- Serine Protease Researcher, 1986-present
- Current research: Extracellular membrane-associated serine proteases prostasin/PRSS8/CAP1, matriptase/MT-SP1/ST14, and hepsin/TMPRSS1
- Teaching "Human Genetics" at UCF, 2010-2024
Making “Sense” of Genetics Today – Karl Chai
- This book returns the Law of Genetics to its simple core in the original discovery and in the applications to genetic studies over the past 120 years, as well as that of today.
- Using classic human hereditary disorders as examples, such as alkaptonuria, sickle cell anemia, Huntington Disease, and cystic fibrosis, the methods of determining the molecular genetic basis of such diseases are outlined.
- The genetics principle at play behind the modern-day “genome-wide association studies” and the variations on the theme is explained for a more sensible and careful evaluation of the findings.
- It provides an overview on some state-of-the-art applications of genetics in modern medicine, and an outlook on the tasks ahead and benefits to expect for mankind.
The book is appropriate for interested readers ranging from students taking genetics courses in high school or college, to scientists and clinicians making sense of the findings from genetic studies.
Karl X. Chai, Ph.D. is a professor at the University of Central Florida, where he has taught Molecular Biology since 1996 and Human Genetics since 2010. He is the author of Interpretive Molecular Biology (2nd ed., 2026) and Making “Sense” of Genetics Today (2024). His research spans human gene cloning, genomics, and epigenetics, including work involving the human kallistatin and B1 bradykinin receptor genes. Dr. Chai earned his Ph.D. in Biochemistry and Molecular Biology from the Medical University of South Carolina and his B.S. in Biochemistry from Peking University.
- B.S. in Biochemistry, 1985, Peking University, Beijing, China
- CUSBEA Class V, 1985 (China-US Biochemistry Examination and Application)
- Ph.D. in Biochemistry and Molecular Biology, 1992, Medical University of South Carolina (MUSC), Charleston
- Postdoctoral fellow, molecular genetics of hypertension, 1992-1996, MUSC
- Molecular cloning of the human kallistatin (PI4/SERPINA4) cDNA and gene
- Assistant Professor - Associate Professor, 1996-present, University of Central Florida (UCF) (College of Medicine)
- Serine Protease Researcher, 1986-present
- Current research: Extracellular membrane-associated serine proteases prostasin/PRSS8/CAP1, matriptase/MT-SP1/ST14, and hepsin/TMPRSS1
- Teaching "Human Genetics" at UCF, 2010-2024