Organic Chemistry II Laboratory Experiments for Chemistry 222

Edition: 2

Copyright: 2025

Pages: 96

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$40.00 USD

ISBN 9798385168378

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The laboratory techniques learned in Chemistry 221 are used to carry out reactions in aromatic substitution, organometallic chemistry, oxidation and reduction chemistry, esterification, and aldol condensations. A significant portion of the semester is devoted to determining the structure of unknown organic compounds, both theoretically in the spectroscopy section and practically in the separation and identification of an unknown compound, as well as verifying the identification of compounds synthesized in a lab. Success in the lab requires careful preparation—you must read the experiment and complete each pre-lab assignment prior to coming to the lab. 

The objectives of the laboratory sessions will provide the learners experience to:

  • work safely and comfortably in the lab
  • gain the experience of executing basic laboratory techniques and the use of modern instrumental methods.
  • make careful qualitative observations and obtain reproduceable quantitative data
  • maintain and keep a complete accurate and well-organized record of experimental laboratory work.
  • be able to evaluate experimental and instrumental data.
  • compile a complete laboratory report that includes valid conclusions based on the evaluation of recorded data.

INTRODUCTION 
LABORATORY CHECK-IN PROCEDURES 
EXPERIMENT 1 Microscale Preparation of Triphenyl Carbinol Using the Grignard Reaction 
EXPERIMENT 2 Microscale Preparation of Camphor 
EXPERIMENT 3 NMR Spectroscopy 
EXPERIMENT 4 Williamson Ether Synthesis 
EXPERIMENT 5 The Microscale Nitration of Acetanilide 
EXPERIMENT 6 The Microscale Reduction of Benzil with Sodium Borohydride 
EXPERIMENT 7 Wittig Reaction: Synthesis of trans-9-(2-Phenylethenyl) Anthracene 
EXPERIMENT 8 The Miniscale Synthesis and Purification of Aspirin 
EXPERIMENT 9 The Microscale Synthesis of Benzopinacolone via a Carbocation Rearrangement 
EXPERIMENT 10 Fischer Esterification 
EXPERIMENT 11 Dibenzalacetone 

APPENDIX D

Rayvon Sneed
Catherine Malele
Edward Miskiel

The laboratory techniques learned in Chemistry 221 are used to carry out reactions in aromatic substitution, organometallic chemistry, oxidation and reduction chemistry, esterification, and aldol condensations. A significant portion of the semester is devoted to determining the structure of unknown organic compounds, both theoretically in the spectroscopy section and practically in the separation and identification of an unknown compound, as well as verifying the identification of compounds synthesized in a lab. Success in the lab requires careful preparation—you must read the experiment and complete each pre-lab assignment prior to coming to the lab. 

The objectives of the laboratory sessions will provide the learners experience to:

  • work safely and comfortably in the lab
  • gain the experience of executing basic laboratory techniques and the use of modern instrumental methods.
  • make careful qualitative observations and obtain reproduceable quantitative data
  • maintain and keep a complete accurate and well-organized record of experimental laboratory work.
  • be able to evaluate experimental and instrumental data.
  • compile a complete laboratory report that includes valid conclusions based on the evaluation of recorded data.

INTRODUCTION 
LABORATORY CHECK-IN PROCEDURES 
EXPERIMENT 1 Microscale Preparation of Triphenyl Carbinol Using the Grignard Reaction 
EXPERIMENT 2 Microscale Preparation of Camphor 
EXPERIMENT 3 NMR Spectroscopy 
EXPERIMENT 4 Williamson Ether Synthesis 
EXPERIMENT 5 The Microscale Nitration of Acetanilide 
EXPERIMENT 6 The Microscale Reduction of Benzil with Sodium Borohydride 
EXPERIMENT 7 Wittig Reaction: Synthesis of trans-9-(2-Phenylethenyl) Anthracene 
EXPERIMENT 8 The Miniscale Synthesis and Purification of Aspirin 
EXPERIMENT 9 The Microscale Synthesis of Benzopinacolone via a Carbocation Rearrangement 
EXPERIMENT 10 Fischer Esterification 
EXPERIMENT 11 Dibenzalacetone 

APPENDIX D

Rayvon Sneed
Catherine Malele
Edward Miskiel