Rumen Health Compendium (soft cover)

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Welcome to the Second Edition of the Rumen Health Compendium. The interval since the release of our First Edition has witnessed profound growth in our comprehension of rumen health and its pivotal role in ruminant production. This journey from the inception to the current iteration of this compendium has been characterized by significant research advancements, technological leaps, and an enriched understanding of the symbiotic relationship between ruminants and their microbial cohorts. 

Ruminants remain unparalleled biomachines, adept at converting human-inedible organic material into valuable, high-quality animal products. Central to this process is the rumen, a complex ecosystem where symbiotic microorganisms orchestrate the breakdown of fibrous plant material into nutrients that sustain ruminant health and productivity. The longstanding evolution of this symbiosis over millions of years underscores its fundamental importance in the ecological and agricultural landscape. 

In this Second Edition, we further explore the contemporary issues in ruminant rearing, with an intensified focus on optimizing rumen health through nutritional strategies. We build upon the foundational knowledge introduced in the First Edition, venturing deeper into the anatomy, physiology, and microbiology of the rumen. We also confront emerging challenges and opportunities in ruminant management, emphasizing the significance of proper ruminant management in reducing the environmental impact of ruminants, particularly concerning global warming. The Second Edition has 26 Chapters, 149 illustrations, and 1,717 references. 

Part 1: Fundamentals of the gastrointestinal tract broadens the discussion from the anatomy and physiology of the rumen (Chapter 1) to encompass the entire gastrointestinal tract (Chapter 2), offering a holistic view of the digestive system. The microbial habitat is dissected into discussions on microbiology (Chapter 3) and fermentation processes (Chapter 4), providing a thorough understanding of the microbial dynamics that drive rumen functionality. 

Part 2: Rumen and host health introduces innovative dietary interventions aimed at modulating rumen function and examines the pathology of ruminal dysfunction. We introduce novel insights on rumen modifiers (Chapters 5 and 6) and provide an in-depth exploration of the rumen epithelium (Chapter 7). The impact of subacute and acute ruminal acidosis (SAARA) on beef (Chapter 8) and dairy (Chapter 9) rumen health, including microbiome composition changes due to SAARA (Chapter 10), is thoroughly discussed. The following chapters address common digestive and metabolic disorders that compromise rumen function, with Chapter 11 focusing on liver abscess management and Chapter 12 on bloat and its microbiome interactions (Chapter 13). Chapter 14 highlights the unique challenges of small ruminants, exploring their peculiarities, while Chapters 15 and 16 look at leaky gut syndrome and hindgut health, respectively, providing comprehensive management strategies. Chapter 17 investigates the connections and implications between rumen health and lung health, emphasizing the interconnectedness of physiological systems. 

Part 3: Toxicity provides a detailed account of plant toxicoses (Chapter 18), microbial toxicoses (Chapter 19), and urea toxicity (Chapter 20), underlining the cause-and-effect relationships between toxic substances and rumen health. 

Part 4: Diagnosis of ruminal dysfunctions offers practical guidance on diagnosing rumen disorders, with chapters dedicated to ruminal fluid analysis (Chapter 21) and fecal examination (Chapter 22), facilitating the assessment and remediation of digestive disorders. 

Part 5: Environment and food safety has new additions, addressing the intersection of rumen health with broader environmental issues such as climate stress (Chapter 23), methane emissions (Chapter 24), food safety (Chapter 25), and antimicrobial resistance (Chapter 26). This section underscores the critical role of the rumen in navigating the sustainability and ethical challenges of ruminant production; understanding the role of the rumen in mediating these challenges becomes increasingly critical. 

Throughout this compendium, we have endeavored to assemble contributions from leading experts across disciplines, ensuring a multidimensional perspective on rumen health and management. Whether you are a seasoned professional or a newcomer to the field, we hope that this compendium will serve as a valuable resource in your quest for knowledge and innovation. 

In closing, we extend our gratitude to the contributors, reviewers, and readers whose collective efforts have shaped this compendium into a beacon of knowledge and insight. May the insights contained within these pages inspire novel discoveries and pave the way toward a healthier, more sustainable future for ruminant production. 

We highly value your feedback and invite suggestions and comments to enhance future editions of the Rumen Health Compendium. Your insights are crucial to our continued improvement and pursuit of excellence in ruminant health research and practice. 

Enjoy your reading journey through the intricate world of rumen health, bolstered by the insights and innovations presented in this Second Edition.

Part 1: Fundamentals of the Gastrointestial Tract

1 Anatomy and Physiology of the Ruminant Forestomach

2 Gastrointestinal Tract Epithelium: Structure, Development, and Adaptation

3 Microbial Habitat: Microbiology of the Rumen

4 Microbial Habitat: Fermentation in the Rumen

Part 2: Rumen and Host Health

5 Rumen Modifiers: Influencing Microbial Fermentation

6 Probiotic and Postbiotic Applications for Ruminants

7 Ruminal Wall Pathology: Rumenitis

8 Subacute Ruminal Acidosis in Beef Cattle

9 Subacute Ruminal Acidosis in Dairy Cattle

10 Effects pf Subacute Ruminal Acidosis on Rumen Microbiota

11 Liver Abscesses in Feedlot Cattle

12 Bloat Management and Prevention

13 Frothy Bloat in Cattle: Ruminal Changes

14 Rumen Functions in Small Ruminants

15 Gut Barrier Structure and Function

16 Hindgut Health

17 Respiratory Microbiome and Respiratory Health: Association with Gut Microbiome

Part 3: Toxicity

18 Pararumenal Pathology and Toxicities

19 Mycotoxicoses

20 Urea and Ammonia Toxicosis

Part 4: Diagnosis of Ruminal Dysfunctions

21 Ruminal Fluid Analysis to Diagnose Dysfunctions of the Rumen

22 Assessing Ruminal Dysfunctions through Fecal Analysis

Part 5: Environment and Food Safety

23 Heat and Cold Stress

24 Methanogenesis in Ruminant Livestock and Opportunities for Mitigation 

25 Enteric Foodbone Pathogens: Shiga toxin-producing E. coli, Salmonella, and Campylobacter

26 Antimicrobial Resistance in the Rumen

References

Luis O. Tedeschi

Luis Tedeschi is a professor in the Department of Animal Science at Texas A&M University. He received his Bachelor of Science degree in Agronomy Engineering and Master of Science degree in Animal and Forage Sciences from the University of São Paulo (Piracicaba, Brazil), and his Doctor of Philosophy degree in Animal Science from Cornell University (Ithaca, NY). His research focuses on the integration of accumulated scientific knowledge of ruminant nutrition into mathematical models to solve contemporary problems. The nutrition models he has developed are being used to develop more efficient production systems while reducing resource use and impact on the environment. He has published more than 250 articles in peer-reviewed journals and book chapters and presented at more than 80 modeling nutrition conferences and workshops worldwide. Tedeschi is a Texas A&M AgriLife Research Faculty Fellow and recipient of the 2011 Sir Frederick McMaster Fellowship and the 2013 J. William Fulbright Scholarship. He received the 2017 American Feed Industry Association in Ruminant Nutrition Research Award and the 2019 Texas A&M University Chancellor EDGES Fellowships. He served on the committee of the 2016 Nutrient Requirement of Beef Cattle by the National Academies of Sciences, Engineering, and Medicine.

T.G. Nagaraja

T. G. Nagaraja is a University Distinguished Professor of Microbiology and Dr. Roy Walter Upham Endowed Professor in the Department of Diagnostic Medicine/Pathobiology in the College of Veterinary Medicine at Kansas State University. His research expertise is in gut microbiology of cattle, particularly of beef cattle. His research program, a blend of basic and applied research, has focused primarily on the role of ruminal microbes in function and dysfunctions of the rumen of cattle, and on food borne pathogens, particularly Shiga toxinproducing Escherichia coli and Salmonella in cattle. Specifically, the contributions that he and his associates have made are in the following areas: antibiotics, particularly ionophores, and ruminal fermentation modifications; etiology and pathogenesis of and vaccine development for liver abscesses; causes and preventions of ruminal acidosis and bloat; ecology of Shiga toxinproducing E. coli and Salmonella in cattle; and antimicrobial resistance and antimicrobial alternatives in cattle production systems. He has mentored 22 PhD, 23 MS, and 4 MPH students and several post docs and visiting scientists. His research has resulted in eight US patents. Nagaraja and his associates have published several book chapters (30), review papers (16), and symposia proceedings (5) and peer-reviewed journal papers (270). His teaching responsibilities include Veterinary Bacteriology and Mycology course for the DVM students, Ruminant Digestive Physiology for the DVM students, two graduate courses on the rumen, Rumen Metabolism and Rumen Microbiology.

Welcome to the Second Edition of the Rumen Health Compendium. The interval since the release of our First Edition has witnessed profound growth in our comprehension of rumen health and its pivotal role in ruminant production. This journey from the inception to the current iteration of this compendium has been characterized by significant research advancements, technological leaps, and an enriched understanding of the symbiotic relationship between ruminants and their microbial cohorts. 

Ruminants remain unparalleled biomachines, adept at converting human-inedible organic material into valuable, high-quality animal products. Central to this process is the rumen, a complex ecosystem where symbiotic microorganisms orchestrate the breakdown of fibrous plant material into nutrients that sustain ruminant health and productivity. The longstanding evolution of this symbiosis over millions of years underscores its fundamental importance in the ecological and agricultural landscape. 

In this Second Edition, we further explore the contemporary issues in ruminant rearing, with an intensified focus on optimizing rumen health through nutritional strategies. We build upon the foundational knowledge introduced in the First Edition, venturing deeper into the anatomy, physiology, and microbiology of the rumen. We also confront emerging challenges and opportunities in ruminant management, emphasizing the significance of proper ruminant management in reducing the environmental impact of ruminants, particularly concerning global warming. The Second Edition has 26 Chapters, 149 illustrations, and 1,717 references. 

Part 1: Fundamentals of the gastrointestinal tract broadens the discussion from the anatomy and physiology of the rumen (Chapter 1) to encompass the entire gastrointestinal tract (Chapter 2), offering a holistic view of the digestive system. The microbial habitat is dissected into discussions on microbiology (Chapter 3) and fermentation processes (Chapter 4), providing a thorough understanding of the microbial dynamics that drive rumen functionality. 

Part 2: Rumen and host health introduces innovative dietary interventions aimed at modulating rumen function and examines the pathology of ruminal dysfunction. We introduce novel insights on rumen modifiers (Chapters 5 and 6) and provide an in-depth exploration of the rumen epithelium (Chapter 7). The impact of subacute and acute ruminal acidosis (SAARA) on beef (Chapter 8) and dairy (Chapter 9) rumen health, including microbiome composition changes due to SAARA (Chapter 10), is thoroughly discussed. The following chapters address common digestive and metabolic disorders that compromise rumen function, with Chapter 11 focusing on liver abscess management and Chapter 12 on bloat and its microbiome interactions (Chapter 13). Chapter 14 highlights the unique challenges of small ruminants, exploring their peculiarities, while Chapters 15 and 16 look at leaky gut syndrome and hindgut health, respectively, providing comprehensive management strategies. Chapter 17 investigates the connections and implications between rumen health and lung health, emphasizing the interconnectedness of physiological systems. 

Part 3: Toxicity provides a detailed account of plant toxicoses (Chapter 18), microbial toxicoses (Chapter 19), and urea toxicity (Chapter 20), underlining the cause-and-effect relationships between toxic substances and rumen health. 

Part 4: Diagnosis of ruminal dysfunctions offers practical guidance on diagnosing rumen disorders, with chapters dedicated to ruminal fluid analysis (Chapter 21) and fecal examination (Chapter 22), facilitating the assessment and remediation of digestive disorders. 

Part 5: Environment and food safety has new additions, addressing the intersection of rumen health with broader environmental issues such as climate stress (Chapter 23), methane emissions (Chapter 24), food safety (Chapter 25), and antimicrobial resistance (Chapter 26). This section underscores the critical role of the rumen in navigating the sustainability and ethical challenges of ruminant production; understanding the role of the rumen in mediating these challenges becomes increasingly critical. 

Throughout this compendium, we have endeavored to assemble contributions from leading experts across disciplines, ensuring a multidimensional perspective on rumen health and management. Whether you are a seasoned professional or a newcomer to the field, we hope that this compendium will serve as a valuable resource in your quest for knowledge and innovation. 

In closing, we extend our gratitude to the contributors, reviewers, and readers whose collective efforts have shaped this compendium into a beacon of knowledge and insight. May the insights contained within these pages inspire novel discoveries and pave the way toward a healthier, more sustainable future for ruminant production. 

We highly value your feedback and invite suggestions and comments to enhance future editions of the Rumen Health Compendium. Your insights are crucial to our continued improvement and pursuit of excellence in ruminant health research and practice. 

Enjoy your reading journey through the intricate world of rumen health, bolstered by the insights and innovations presented in this Second Edition.

Part 1: Fundamentals of the Gastrointestial Tract

1 Anatomy and Physiology of the Ruminant Forestomach

2 Gastrointestinal Tract Epithelium: Structure, Development, and Adaptation

3 Microbial Habitat: Microbiology of the Rumen

4 Microbial Habitat: Fermentation in the Rumen

Part 2: Rumen and Host Health

5 Rumen Modifiers: Influencing Microbial Fermentation

6 Probiotic and Postbiotic Applications for Ruminants

7 Ruminal Wall Pathology: Rumenitis

8 Subacute Ruminal Acidosis in Beef Cattle

9 Subacute Ruminal Acidosis in Dairy Cattle

10 Effects pf Subacute Ruminal Acidosis on Rumen Microbiota

11 Liver Abscesses in Feedlot Cattle

12 Bloat Management and Prevention

13 Frothy Bloat in Cattle: Ruminal Changes

14 Rumen Functions in Small Ruminants

15 Gut Barrier Structure and Function

16 Hindgut Health

17 Respiratory Microbiome and Respiratory Health: Association with Gut Microbiome

Part 3: Toxicity

18 Pararumenal Pathology and Toxicities

19 Mycotoxicoses

20 Urea and Ammonia Toxicosis

Part 4: Diagnosis of Ruminal Dysfunctions

21 Ruminal Fluid Analysis to Diagnose Dysfunctions of the Rumen

22 Assessing Ruminal Dysfunctions through Fecal Analysis

Part 5: Environment and Food Safety

23 Heat and Cold Stress

24 Methanogenesis in Ruminant Livestock and Opportunities for Mitigation 

25 Enteric Foodbone Pathogens: Shiga toxin-producing E. coli, Salmonella, and Campylobacter

26 Antimicrobial Resistance in the Rumen

References

Luis O. Tedeschi

Luis Tedeschi is a professor in the Department of Animal Science at Texas A&M University. He received his Bachelor of Science degree in Agronomy Engineering and Master of Science degree in Animal and Forage Sciences from the University of São Paulo (Piracicaba, Brazil), and his Doctor of Philosophy degree in Animal Science from Cornell University (Ithaca, NY). His research focuses on the integration of accumulated scientific knowledge of ruminant nutrition into mathematical models to solve contemporary problems. The nutrition models he has developed are being used to develop more efficient production systems while reducing resource use and impact on the environment. He has published more than 250 articles in peer-reviewed journals and book chapters and presented at more than 80 modeling nutrition conferences and workshops worldwide. Tedeschi is a Texas A&M AgriLife Research Faculty Fellow and recipient of the 2011 Sir Frederick McMaster Fellowship and the 2013 J. William Fulbright Scholarship. He received the 2017 American Feed Industry Association in Ruminant Nutrition Research Award and the 2019 Texas A&M University Chancellor EDGES Fellowships. He served on the committee of the 2016 Nutrient Requirement of Beef Cattle by the National Academies of Sciences, Engineering, and Medicine.

T.G. Nagaraja

T. G. Nagaraja is a University Distinguished Professor of Microbiology and Dr. Roy Walter Upham Endowed Professor in the Department of Diagnostic Medicine/Pathobiology in the College of Veterinary Medicine at Kansas State University. His research expertise is in gut microbiology of cattle, particularly of beef cattle. His research program, a blend of basic and applied research, has focused primarily on the role of ruminal microbes in function and dysfunctions of the rumen of cattle, and on food borne pathogens, particularly Shiga toxinproducing Escherichia coli and Salmonella in cattle. Specifically, the contributions that he and his associates have made are in the following areas: antibiotics, particularly ionophores, and ruminal fermentation modifications; etiology and pathogenesis of and vaccine development for liver abscesses; causes and preventions of ruminal acidosis and bloat; ecology of Shiga toxinproducing E. coli and Salmonella in cattle; and antimicrobial resistance and antimicrobial alternatives in cattle production systems. He has mentored 22 PhD, 23 MS, and 4 MPH students and several post docs and visiting scientists. His research has resulted in eight US patents. Nagaraja and his associates have published several book chapters (30), review papers (16), and symposia proceedings (5) and peer-reviewed journal papers (270). His teaching responsibilities include Veterinary Bacteriology and Mycology course for the DVM students, Ruminant Digestive Physiology for the DVM students, two graduate courses on the rumen, Rumen Metabolism and Rumen Microbiology.