Understanding Cancer: From Discovery to Therapy
Edition: 2
Copyright: 2022
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Cancer is a complex disease, and the study of cancer requires an understanding of molecular and cellular biology, pathology, clinical aspects and an introduction to the therapeutics that are currently in use. In this book, we first discuss the molecular and cellular changes that occur in most carcinomas. This is followed by a brief overview of experimental approaches to studying cancer and clinical aspects of diagnosis and treatment. Next, we bring together these components of cancer to focus on some of the most common and deadly cancers. By the end of the book, students will possess a strong understanding of both the basic biology of cancer as well as relevant clinical, therapeutic and ethical issues of the disease.
Chapter 1: History and Overview
Chapter 2: Cells and Tissues
Chapter 3: Growth Factors and cell cycle
Chapter 4: Apoptosis and Immortality
Chapter 5: Angiogenesis, cancer stem cells and metastasis
Chapter 6: Screening, Diagnosis, and Treatments
Chapter 7: Experimental Techniques in Cancer Biology
Chapter 8: Hormonally Driven Cancers: Breast and Prostate Cancer
Chapter 9: Brain Cancer and Metastatic Cancer to the Brain
Chapter 10: Cervical, Hepatocellular, and Gastric Carcinomas: Infectious Agents and Cancer
Chapter 11: Colorectal Cancer: Developmental Pathways and Commensals
Chapter 12: Modern Carcinogens: Lung Cancer
Chapter 13: Skin Cancer: Role of Immunity in Cancer Progression
Chapter 14: Pancreatic Cancer: Ras Mutations
Chapter 15: Leukemia and Lymphoma: Targeted Therapeutics
Joyce A. Schroeder, PhD is a Professor in the Department of Molecular & Cellular Biology at the University of Arizona, Tucson, and a leading researcher in cancer biology, particularly breast cancer and immune modulation.